The short answer is that glyphosate, the active ingredient in Roundup, binds to and removes minerals that make both humans and the plants they eat healthy. This is not good.
Glyphosate binds with calcium, magnesium, manganese, iron, molybdenum, cobalt and boron. Boron is needed in the cell wall of plants to protect them from diseases and pests. Boron is crucial just after germination to help the young seedling grow roots into the soil. And later boron is needed for pollination. Graeme Sait once consulted with an Australian farmer who had $7 million in crop losses due to a boron deficiency. The farmer was so desperate that he was renting bee hives from a beekeeper. All the man needed was to do a cheap foliar spray on his corn stalks with boron.
https://earthnewspaper.com/glyphosate-bad-for-human-and-plant-health-by-video-rebel
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Just buy borax at the supermarket.